Sleep Apnea and Autonomic Cerebrovascular Dysfunction

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Association of autonomic dysfunction and mild obstructive sleep apnea.

BACKGROUND Autonomic dysfunction (AD) has been independently associated with obstructive sleep apnea (OSA). Autonomic abnormalities are generally considered to be secondary to OSA. Autonomic dysfunction may also contribute to OSA. If AD contributes to OSA, we postulated that abnormalities may be present in mild OSA where the confounding causal effects of hypoxemia and sleep disruption are reduc...

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Cerebrovascular Consequences of Obstructive Sleep Apnea

O bstructive sleep apnea (OSA) is defined by interrupted breathing during sleep due to airway obstruction with an ongoing respiratory effort. In adults, OSA most commonly is caused by decreased muscle tone (required for patency) in the soft tissues of the upper airway. Symptoms of OSA include snoring, daytime sleepiness, morning headache, sexual dysfunction, and mood and behavioral disorders. A...

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Neuropsychological dysfunction in sleep apnea.

To evaluate the effect of intermittent hypoxemia on neuropsychological functioning, neuropsychological tests were administered to 14 sleep apnea patients, a control group of 10 patients with other disorders of excessive somnolence, and another control group of 14 healthy volunteers. The sleep disorder groups were matched on two measures of sleepiness. It was found that sleep apnea patients perf...

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Model-based studies of autonomic and metabolic dysfunction in sleep apnea.

Obesity and insulin resistance are highly prevalent in subjects diagnosed with sleep apnea. One factor common to obesity, sleep and insulin resistance is autonomic nervous system dysfunction, in particular, sympathetic overactivity. Although the causal links among these factors are not well understood, it is likely that the vicious cycle of interplay among these factors predisposes to the emerg...

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[Obstructive sleep apnea and erectile dysfunction].

Erectile dysfunction (ED) is common among men with obstructive sleep apnea (OSA) with reports of prevalence varying from 30 – 50 percent. The mechanism is unknown. Since chronic hypoxia is known to cause peripheral neuropathies, it is logical to question whether ED in OSA might reflect peripheral neuropathy resulting from the intermittent nocturnal hypoxia concomitant with OSA. Two recent studi...

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ژورنال

عنوان ژورنال: Sleep

سال: 1987

ISSN: 0161-8105,1550-9109

DOI: 10.1093/sleep/10.1.25